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Synthesis and Characterization of 4-Indolylcyanamide: A Potential IR Probe for Local Environment.

Molecules · 2025 · PMC12566075 · PMID 41157080

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a clear trendno p-value reported
In aprotic solvents such as DMSO, DMF, tetrahydrofuran (THF), 1,4-dioxane, cyclopentanone, and acetonitrile (ACN), a clear trend is observed: the higher the solvent’s β value, the lower the ω (NHCN) vibrational frequency (i.e., a shift to lower wavenumbers, referred to as a red shift).

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