Novel 1-(2-Aryl-2-adamantyl)piperazine Derivatives Exhibit In Vitro Anticancer Activity Across Various Human Cancer Cell Lines, with Selective Efficacy Against Melanoma.

Under the tested experimental conditions, compound 6 did not alter GβL protein levels compared to the control (see Figure 7 a,e), whereas treatment with 20 μM of compound 7 reduced GβL protein levels, though this reduction did not reach statistical significance (see Figure 7 b,f).

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