Efficacy of Lamotrigine in the Treatment of Unipolar and Bipolar Depression: Meta-Analysis of Acute and Maintenance Randomised Controlled Trials.

Pharmaceuticals (Basel) · 2025 · PMC12567274 · PMID 41155702

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did not reach statistical significanceno p-value reported

There was a marginal clinical advantage of adding lamotrigine to mood stabilisers or quetiapine that did not reach statistical significance (N = 375; SMD: 0.88; CI: −0.41, 2.18).

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