A Polysaccharide-Rich Ingredient from <i>Hypericum perforatum</i> L. Ameliorates Depression-like and Post-Traumatic Stress Disorder-like Symptoms in Mouse Models.

On day 8, post hoc analysis indicated that HPP2 at 50, 200, and 800 mg/kg doses produced notable effects on the immobility time in the FST ( p < 0.01), and the LYT_150 group also exhibited a gradual decrease compared to the control group, although this decrease did not reach statistical significance ( Figure 3 K; p = 0.082).

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The 50 mg/kg dose shortened immobility but did not achieve significance ( p > 0.1). 3.4.

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