Endothelial βII Spectrin Deletion Exacerbates Inflammation and Impairs Tissue Regeneration in Ischemic-Diabetic Skin Wound Healing.

(A–D) Comparison for cell counts from flow cytometry for total immune cells (CD45+), neutrophils, monocytes and Ly‐6C high monocytes between the two groups on Day 4 post‐wounding (D4 PW); Sptbn1 flox/flox (beige; n = 5 mice) and Sptbn1 ECKO (blue; n = 8 mice) suggest an increasing trend in the Sptbn1 ECKO mice group (plotted mean ± SEM with respective p ‐values).

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While the knockout mice showed a trend toward increased wound width, the differences were not statistically significant, possibly due to variability in initial wound size.

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