For eGFR, there was a highly significant overall association ( p ‐overall < 0.001), and the curve displayed an apparent N‐shaped pattern, with an initial increase in eGFR followed by a decrease.
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Effect of EGCG Intake on Kidney Function Chronic Kidney Disease: A Nonlinear Dose-Response Relationship and Health Impact Evidence From US Adults.
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The sentences
However, the test for nonlinearity did not reach statistical significance ( p ‐nonlinear = 0.063), indicating that the observed pattern was not statistically robust.