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Mesenchymal stem cells inhibit mitochondrial fission by upregulating armadillo repeat containing 1, ameliorating oxidative stress in renal fibrosis.

Stem Cell Res Ther · 2025 · PMC12570658 · PMID 41153008

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The upregulation of ARMC1 protein in renal tissue was also better than that in the Apocynin and Mdivi-1 intervention groups, and the inhibition of mitochondrial fission DRP1 protein was not worse than that in the Mdivi-1 or Apocynin intervention group, although it did not reach statistical significance (Fig. 8 ).

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