nominally significantP > 0.05
By removing each SNP from the MR analysis sequentially, if the association is no longer nominally significant ( P > 0.05) with the SNP removed, this indicates that a particular SNP is driving the association.
By removing each SNP from the MR analysis sequentially, if the association is no longer nominally significant ( P > 0.05) with the SNP removed, this indicates that a particular SNP is driving the association.