Non-linear association between Life's Essential 8 and diabetic retinopathy: mediating role of depression in US adults with diabetes.

BMC Public Health · 2025 · PMC12573860 · PMID 41163192

Europe PMC DOI

hedged sentences

0.0002

closest p · 0.0× alpha

0.0972

boldest claim

The sentences

highly significantP = 0.0002actually significant

Results Participants characteristics The PIR exhibited a highly significant correlation with the risk of DR ( P = 0.0002).

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did not reach statistical significanceP = 0.0972so close (0.05 < p ≤ 0.1)

However, above this threshold, the protective effect of LE8 scores increased slightly but did not reach statistical significance (OR2, 1.06; 95% CI, 0.99–1.14, P = 0.0972) (Table 4 ).

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