PEEP-AKI-COVID ICU: Effect of positive end-expiratory pressure on acute kidney injury development in patients with COVID-19-associated acute respiratory distress syndrome: an ancillary analysis of the COVID-ICU study.

Sensitivity analysis using severe AKI definition When AKI was defined as KDIGO stage 2 or 3 and models were adjusted for confounding factors, PEEP was associated with the development of AKI, although this association did not reach statistical significance (odds ratio [OR] 1.06; 95% confidence interval [CI], 1.00–1.13) (Supplementary Fig. 1).

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