Clonally expanded effector CD4<sup>+</sup> cytotoxic T lymphocytes are associated with severe neurological adverse events after immune checkpoint inhibitor therapy.

J Immunother Cancer · 2025 · PMC12574404 · PMID 41167637

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did not reach statistical significanceno p-value reported

These changes collectively resulted in a lower B cell maturity score in n-irAE patients, with an MFC of 0.52 compared with the control group, although this difference did not reach statistical significance ( online supplemental figure 3E ).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.

Clonally expanded effector CD4&lt;sup&gt;+&lt;/sup&gt; cytotoxic T lymphocytes are associated with severe neurological adverse events after immune checkpoint inhibitor therapy.

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Clonally expanded effector CD4<sup>+</sup> cytotoxic T lymphocytes are associated with severe neurological adverse events after immune checkpoint inhibitor therapy.