Risk factors for aggravated COVID-19 despite medical care after admission among Japanese patients: A Japanese association for infectious diseases COVID registry study.

PLoS One · 2025 · PMC12574867 · PMID 41166325

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did not reach statistical significanceno p-value reported

In contrast to earlier reports, underlying conditions such as diabetes, chronic heart failure, and chronic kidney disease—previously identified as aggravating factors in other populations—did not reach statistical significance in this cohort [ 4 , 19 , 20 ].

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