Identification of natural Zika virus peptides presented on the surface of paediatric brain tumour cells by HLA class I.

PLoS One · 2025 · PMC12574884 · PMID 41166287

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a clear trendno p-value reported

A clear trend can be observed when protein abundances are considered alongside the ZIKV peptide number ( Fig 3B , Table 3 ).

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highly significantno p-value reported

Using the Enrichr tool, we identified several pathway repositories in which immune-system related categories were highly significant: (i) NCATS BioPlanet - ‘Immune System’ and ‘Antigen Presentation’ categories were ranked 2 nd and 7 th (with adjusted p-values of 2.4 x 10 -5 and 1.3 x 10 -4) and (ii) Panther DB in which ‘T-cell activation’ was the 2 nd most significant category (p = 0.0071) [ 27 , 28 ] ( S1 File ).

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