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Human epidermal growth factor receptor 2 overexpression is associated with high-grade tumors in upper tract urothelial carcinoma.

World J Clin Oncol · 2025 · PMC12576524 · PMID 41178915

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The distribution across T stages indicated a moderately higher HER2 positivity in non-muscle-invasive (≤ T1) tumors (55.6%) than in muscle-invasive tumors (T2: 41.9%, ≥ T3: 43.6%), although these differences did not reach statistical significance.

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