Dysregulation of the endocannabinoid system - a key factor in the progression of multiple sclerosis?

J Med Life · 2025 · PMC12577783 · PMID 41178906

Europe PMC DOI

hedged sentence

0.0919

closest p · 1.8× alpha

0.0919

boldest claim

The sentences

did not reach statistical significanceP = 0.0919so close (0.05 < p ≤ 0.1)

For AEA, the overall ANOVA approached but did not reach statistical significance (F(2,27) = 2.625, P = 0.0919); post-hoc pairwise comparisons revealed a trend toward lower AEA concentrations in the treatment-naive RRMS group compared with healthy controls (mean difference = −5.95 ng/ml, SE = 2.66; P = 0.098).

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