Barely Significant
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Seeding Alzheimer's disease-associated tau pathology in MAPT knock-in primary neurons causes early axonopathy and synaptic dysfunction.

Sci Rep · 2025 · PMC12578843 · PMID 41173863

Europe PMCDOI
1
hedged sentence
0.0590
closest p · 1.2× alpha
0.0590
boldest claim

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did not reach statistical significancep = 0.059so close (0.05 < p ≤ 0.1)
Within the PBS cultures, Glu caused a 72% increase in neuronal network burst frequency compared to baseline, but this did not reach statistical significance ( p = 0.059; Fig. 8 B).

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