Identification and experimental verification of necroptosis-related prognostic gene signature and characterization of tumor immune infiltration in lung squamous cell carcinoma.

In the multivariate model, the risk score retained significance as an independent prognostic factor (HR = 2.76, P = 0.0012), while the pTNM stage showed only borderline significance (HR = 1.60, P = 0.01) ( Figs. 5A , 5B ).

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Kaplan–Meier curves showed a trend toward reduced overall survival in the high-risk group, although statistical significance was not reached ( Fig. 9E ).

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