Normal adrenocorticotropic hormone levels do not exclude adrenal insufficiency during immune checkpoint inhibitor therapy: evidence from clinical, steroid, and structural analyses.

Front Endocrinol (Lausanne) · 2025 · PMC12580128 · PMID 41189622

Europe PMC DOI

hedged sentence

0.5500

closest p · 11.0× alpha

0.5500

boldest claim

The sentences

did not reach statistical significancep = 0.55not close (p > 0.1)

Longer time to IAD onset and a greater number of ICI treatments were observed in the ACTH-preserved group, although the differences did not reach statistical significance (p = 0.55 and p = 0.11, respectively).

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