In internal replication, all the newly identified loci were nominally significant both in East Asian and European populations (Supplementary Fig. 7b and Supplementary Data 25 ). rs35593046 ( CACNA1D ), rs7659823 ( EDNRA ), rs5823966 ( ZNF397 ), and rs1541596 ( CARM1 ) were much more frequently observed in the East Asian population (Supplementary Fig. 7c and Supplementary Data 25 ).
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Genome-wide analysis of heart failure yields insights into disease heterogeneity and enables prognostic prediction in the Japanese population.
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