Barely Significant
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Stepwise dose reduction and discontinuation of bDMARD in rheumatoid arthritis: a prospective cohort study of flare-free population, flares, and predictive markers.

Arthritis Res Ther · 2025 · PMC12584375 · PMID 41189003

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showed a trendno p-value reported
Similarly, in Phase 2, RF-positive patients showed a trend toward lower flare-free population rates compared with RF-negative patients; however, the difference was not statistically significant (Fig. 2 E).

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