Kidney clearances of protein-bound uremic toxins predict outcomes in chronic kidney disease: a prospective cohort study.

Ren Fail · 2025 · PMC12584829 · PMID 41183791

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did not reach statistical significanceno p-value reported

Notably, reduced kidney clearance of pCS or hippurate was linked to an increased risk of mortality, independent of eGFR, in a CKD cohort utilizing overnight urine samples (IQR, 11–14 h), but HR of lower IS clearance did not reach statistical significance [ 19 ].

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