Elevated TyG-BMI significantly increases the 1-year stroke recurrence risk in patients with acute ischemic stroke and hypertension.

Front Endocrinol (Lausanne) · 2025 · PMC12585975 · PMID 41199859

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Conversely, in women (n=642), each 10-unit TyG-BMI increase markedly elevated the risk of 1-year stroke recurrence (adjusted HR = 1.18, 95% CI:1.07–1.29, P < 0.001), with quartile analysis demonstrating a robust dose-response effect: Q3 (HR = 8.81, 95% CI 2.22–34.79, P = 0.002) and Q4 (HR = 5.79, 95% CI 1.49–22.56, P = 0.011) vs Q1, alongside a significant trend (P for trend = 0.002). 3.5.

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