Predictive Accuracy of First-Trimester Biochemical and Clinical Markers in the Early Identification of Gestational Diabetes Mellitus: A Prospective Observational Study.

Cureus · 2025 · PMC12586195 · PMID 41200603

Europe PMC DOI

hedged sentences

0.0001

closest p · 0.0× alpha

0.0540

boldest claim

The sentences

highly significantp < 0.0001actually significant

The full model incorporating uric acid, CRP, and PPBS further increased predictive accuracy with R2 = 0.790 and was highly significant (p < 0.0001).

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did not reach statistical significancep = 0.054so close (0.05 < p ≤ 0.1)

Uric acid alone showed minimal predictive ability (R2 = 0.001, p = 0.876), while the combination of uric acid and CRP slightly improved prediction but did not reach statistical significance (R2 = 0.042, p = 0.054).

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