Sex differences in the efficacy of GLP-1 receptor agonists: A systematic review and meta-analysis of cardiovascular and renal outcome trials.

Diabetes Obes Metab · 2025 · PMC12587241 · PMID 40932012

Europe PMC DOI

hedged sentences

0.7000

closest p · 14.0× alpha

0.7000

boldest claim

The sentences

a nonsignificant trendp = 0.70not close (p > 0.1)

Hospitalisation for HF In males, GLP‐1RAs showed a nonsignificant trend towards reducing HHF (HR: 0.95; 95% CI: 0.75–1.21; I 2 = 16%; p = 0.70).

also in 5,406 other papers

did not reach statistical significanceno p-value reported

While variations between sexes were observed in certain outcomes, these differences did not reach statistical significance for interaction.

also in 111,027 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.