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An SGLT2 inhibitor, canagliflozin, reduces blood glucose level in the renal capillaries and protects the capillary network in the diabetic rats.

Diabetes Obes Metab · 2025 · PMC12587256 · PMID 40926738

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In contrast, the effect of insulin on RV/A ratio and RecA1 staining did not reach statistical significance compared to the vehicle group.

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