Connectivity as a universal predictor of tau progression in atypical Alzheimer's disease.

Brain · 2025 · PMC12588720 · PMID 40810361

Europe PMC DOI

hedged sentences

0.0700

closest p · 1.4× alpha

0.1160

boldest claim

The sentences

borderline significantP = 0.07so close (0.05 < p ≤ 0.1)

Paired Wilcoxon signed-rank tests for the entire atypical AD group were significant ( P < 0.05) for all quartile comparisons, except for quartile 2 versus quartile 3, which was borderline significant ( P = 0.07).

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did not reach statistical significanceP = 0.116not close (p > 0.1)

Although the analysis did not reach statistical significance, the direction of this effect was confirmed in the smaller UCSF replication sample ( n = 30), β = 0.36, P = 0.116 ( Supplementary Fig. 5 ).

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