PSMA radioligand uptake correlates with PSMA expression in high-grade glioma and brain metastasis: insights from a prospective PET-MRI guided multiregional biopsy study.

Eur J Nucl Med Mol Imaging · 2025 · PMC12589371 · PMID 40414994

Europe PMC DOI

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0.5200

closest p · 10.4× alpha

0.5200

boldest claim

The sentences

did not reach statistical significanceP = 0.52not close (p > 0.1)

At the location of BM samples with PSMA-positive microvessels, [ 68 Ga]Ga-PSMA-11 uptake was higher compared to areas from samples without PSMA-positive microvessels, but did not reach statistical significance (SUVmax median, range: 6.1, 4.3–12.2 versus 4.8, 2.9–10.6, P = 0.52).

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