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Antioxidant and oxidative enzymes, genetic variants, and cofactors as prognostic biomarkers of COVID-19 severity and mortality: a systematic review.

Front Mol Biosci · 2025 · PMC12590006 · PMID 41209585

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showed a trendno p-value reported
Meanwhile, another NOS3 polymorphism—the 27-bp VNTR (4b/a)—showed a trend toward association in younger patients (≤50 years) without COPD, with the 4b allele and 4b/4b genotype more frequent in severe cases (p values around 0.06–0.07), though these findings did not reach conventional statistical significance. 4.3 Master regulators of antioxidant response and their geneti

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