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The impact of tetrahydrocannabinol on central pain modulation in chronic pain: a randomized clinical comparative study of offset analgesia and conditioned pain modulation in fibromyalgia.

J Cannabis Res · 2025 · PMC12590702 · PMID 41199355

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Although trends were evident in the association between CPM and treatment response, these did not reach statistical significance, highlighting the need for further investigation in larger cohorts.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.