Human iPSC-Derived Mononuclear Phagocytes Improve Cognition and Neural Health across Multiple Mouse Models of Aging and Alzheimer's Disease.

Thus, there appears to be an overall trend, where animals with higher levels of serum amyloid proteins perform worse at the novel object location task and have lower levels of mossy cells.

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Using the novel object recognition task to assess recognition memory showed that aging mice had a trend toward decreased time spent with a novel object, but this did not reach statistical significance (Figure 1I ).

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