Longitudinal awake imaging of mouse deep brain microvasculature with super-resolution ultrasound localization microscopy.

Figure 2d shows a clear trend of decreasing MB concentration in the blood stream and increasing cumulative MB count with time.

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Figure 4f further illustrates the change in mean velocity within the selected ROI, where both arteries and veins showed a decreasing trend; however, venous flow velocity reduced by an average of 38%, compared to a 19% reduction in arterial flow velocity across the cortical ROI.

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