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Iron chelation as a therapeutic target in vanadium neurotoxicity and Parkinson's disease: role of medicinal plants.

Front Neurol · 2025 · PMC12591949 · PMID 41211282

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When intermittent SP treatment of vanadium exposed flies was restricted to only the second week, the effect on survival was not as significant as when the intermittent treatment started from the first week ( Figure 6 ), and the antioxidant thiol level showed a trend toward improvement relative to the vanadium only group. 3 Discussion Iron plays a role in the major cellular pathologies associated with PD ( 26 ) and the ability to chelate iron is useful to select plant species for further evaluation as a potential therapeutic agent in PD.

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