Subtypes of multiple-etiology dementias and the heterogeneous impact of APOE variants.

Although the groups of individuals who died with AD and CAA co‐pathology (e.g., AD+VaD+CAA, AD+VaD+CAA+LBD, AD+VaD+CAA+TauTDP, AD+VaD+CAA+HipSc, and AD+VaD+CAA+LBD+TauTDP) had the highest SHRs for mortality risk associated with APOE ε4, the association did not reach statistical significance in the competing risk groups of AD alone and some other groups with AD but without CAA neuropathology (e.g., AD+VaD+LBD, AD+VaD+TauTDP) as shown in Figure 4 .

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