Epidermal Growth Factor Receptor Exon 20 Insertion in Early Resected Non-Small Cell Lung Cancer: A Retrospective, Single-Center Study in Taiwan.

J Chest Surg · 2025 · PMC12592020 · PMID 40851479

Europe PMC DOI

hedged sentence

0.2240

closest p · 4.5× alpha

0.2240

boldest claim

The sentences

did not reach statistical significancep=0.224not close (p > 0.1)

Using wild-type EGFR as the reference, patients with exon 20 insertions had a significantly increased risk of mortality (OS: hazard ratio [HR], 3.223; 95% confidence interval [CI], 1.271–8.170; p=0.014), though their increased risk of recurrence did not reach statistical significance (DFS: HR, 1.760; 95% CI, 0.708–4.377; p=0.224).

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