Acinar-specific loss of activating transcription factor 3 restricts KRAS<sup>G12D</sup> mediated transcriptional changes and PanIN progression.

In total, 78.2% of all DEGs between Ptf1a creERT/+ Kras G12D/+ and WT acini did not reach statistical significance in differential expression between wild type and APK acini (Fig. 1F and Supplemental Table S1 ).

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