Platelet count and sleep quality in immune thrombocytopenia: correlation with 5-hydroxytryptamine and therapeutic implications of platelet-5-HT-melatonin axis dysregulation.

Beyond these primary parameters, analogous trends were observed across other PSQI components: patients with platelet counts <50 × 10 9 /L tended to report longer sleep latency, more sleep disturbances, increased use of sleep medications, and worse subjective sleep quality, although these differences did not reach statistical significance ( Supplementary Figures S2a–d ).

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