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Lung Cancer Cell-intrinsic Asparagine Synthetase Potentiates Anti-Tumor Immunity via Modulating Immunogenicity and Facilitating Immune Remodeling in Metastatic Tumor-draining Lymph Nodes.

Int J Biol Sci · 2025 · PMC12594603 · PMID 41208878

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a slight trendno p-value reported
We observed that high expression of ASNS correlated with better prognosis in NSCLC patients, as evidenced by a slight trend of longer OS in the TCGA dataset for LUSC although it did not reach statistical significance, as well as longer DFS in the TCGA dataset for NSCLC and LUAD ( Supplemental Figure 11 A-F ).

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