a trend toward significancep < 0.1
Those proteins that had both a trend toward significance ( p < 0.1) and a log 2 fold change > ±0.5 detected in the mutant compared to WT-overexpressing cells are shown in Figure S3 .
Those proteins that had both a trend toward significance ( p < 0.1) and a log 2 fold change > ±0.5 detected in the mutant compared to WT-overexpressing cells are shown in Figure S3 .
Interestingly, we observed either a strong trend or significant decreases in total protein expression within the synaptoneurosome and PSD fractions when normalized to the total protein in the homogenate.