Barely Significant
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Tyrosine Kinase Inhibitors Outperform Immune Checkpoint Inhibitors in Bone-Predominant Metastatic Renal Cell Carcinoma: A Multicenter Real-World Analysis.

J Cancer · 2025 · PMC12595247 · PMID 41210691

1
hedged sentence
0.0750
closest p · 1.5× alpha
0.0750
boldest claim

The sentences

did not reach statistical significanceP = 0.075so close (0.05 < p ≤ 0.1)
Although this difference did not reach statistical significance (log-rank test, P = 0.075), it suggests a potential benefit of TKIs in delaying disease progression.

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