Kinetic Analysis of HDAC- and Sirtuin-Mediated Deacylation on Chemically Defined Histones and Nucleosomes.

Curr Protoc · 2025 · PMC12595542 · PMID 41204805

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a clear trendno p-value reported

However, due to the inherent challenges of histone protein assays (described in Basic Protocol 2 ), obtaining a clear trend in a series of deacylation assays on free histone proteins is even more difficult.

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