A Prospective Pilot Study to Investigate Whether Donor-Derived Cell-Free DNA Can Be Used as a Biomarker of Recurrent IgA Nephropathy Post-Kidney Transplantation.

Although transplanted patients with IgAN recurrence had a lower eGFR compared to those without recurrence, the difference did not reach statistical significance (43 [IQR 19–54] vs. 57.5 mL/min/1.73 m 2 [IQR 50–70.5], p = 0.10) (Figure 2 ) The ROC curve analysis showed that proteinuria (AUC = 0.96 [95% CI 0.87–1.00], p = 0.002) and eGFR (AUC = 0.74 [95% CI 0.47–1.00], p = 0.09) had superior discrimination for IgAN recurrence compared to %dd‐cfDNA (AUC = 0.57 [95% CI 0.28–0.85], p = 0.64) (Figure 3 ). 4.

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