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Mechanistic effects of percutaneous needle fasciotomy combined with stretching on early-stage skeletal muscle fibrosis in rats: focus on the TGF-β1/Smad signaling pathway.

J Orthop Surg Res · 2025 · PMC12595653 · PMID 41204339

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While the imm + PNF + Str group showed a significant decrease in collagen III expression in comparison with the Imm group ( P < 0.01), the reduction in the imm + Apu + Str group failed to reach statistical significance (Fig. 4 B–D).

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