Development of programmable RNA imaging with RNA-guided GFP via click chemistry.

Nucleic Acids Res · 2025 · PMC12597101 · PMID 41206045

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showed a trendno p-value reported

Regarding further modification to enhance nuclease resistance, incorporating phosphorothioate (PS) modifications to all bases of DBCO-RNA/DNA in RGG/DGG showed a trend towards increased RNA imaging efficiency, although the difference was not statistically significant.

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