Sex-specific metabolic effects of Treg expansion in db/db mice.

Front Immunol · 2025 · PMC12597972 · PMID 41221275

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a clear trendno p-value reported

Notably, the anti-inflammatory cytokines Il10 and Il13 displayed a clear trend toward increased expression in Treg-expanded animals ( Figures 4E, F , respectively). 4.

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a mild trendno p-value reported

Pparγ , which was elevated in diabetic animals, showed a mild trend toward reduction after Treg expansion, again more evident in females ( Figure 4D ).

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