A nonsignificant trend toward a decrease was found upon LPS exposure ( S6C ii Fig ).
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RNA-binding protein IMP1/ZBP1 directs local translation in microglial processes to regulate motility and phagocytosis during inflammation.
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Whereas siRNA #1-transfected cells showed a trend toward a decrease in IMP1/ZBP1 levels after 24-h transfection, siRNA #2 significantly downregulated the target protein both at 6 and 24 h ( S6E Fig ).