IGHV1 usage is associated with lymphadenopathy and aggressive disease in the TCL1 mouse model for chronic lymphocytic leukemia.

Sci Rep · 2025 · PMC12603018 · PMID 41214147

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0.1200

closest p · 2.4× alpha

0.1200

boldest claim

The sentences

did not reach statistical significancep = 0.12not close (p > 0.1)

Higher clonal fractions were observed for IGHV1 CLL clones compared to IGHV11 (median: IGHV1: 79%; IQR: 57–97%; IGHV11: 48%; IQR: 45–71%), although the difference did not reach statistical significance ( p = 0.12; Supp.

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