showed a trendp = 0.088
In these adjusted models, PES remained a significant predictor of increased NRM (HR 1.46, 95% CI 1.22–1.75; p < 0.001), was independently associated with a lower risk of relapse (HR 0.78, 95% CI 0.63–0.96; p = 0.020), and showed a trend toward inferior OS (HR 1.13, 95% CI 0.98–1.30; p = 0.088) (Table 3 ).