Barely Significant
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Plasma-Based Genomic Features Influencing Outcomes of T790M-Positive Non-Small Cell Lung Cancer Receiving Osimertinib.

Cancer Med · 2025 · PMC12605980 · PMID 41221800

Europe PMCDOI
2
hedged sentences
0.0590
closest p · 1.2× alpha
0.0590
boldest claim

The sentences

showed a trendp = 0.059so close (0.05 < p ≤ 0.1)
Similar to the findings in all 64 patients, female patients showed a trend toward longer mPFS ( p = 0.059) and mOS ( p = 0.091).

also in 53,322 other papers

highly significantno p-value reported
The clinical implications of plasma‐based detection of T790M are highly significant.

also in 132,142 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.