Mapping the stage-specific plasma p53 interactome reveals colorectal cancer progression signatures and therapeutic vulnerabilities.

J Liq Biopsy · 2025 · PMC12606009 · PMID 41234384

Europe PMC DOI

hedged sentence

0.2086

closest p · 4.2× alpha

0.2086

boldest claim

The sentences

did not reach statistical significancep = 0.2086not close (p > 0.1)

Although its transcriptomic enrichment did not reach statistical significance (adjusted p = 0.2086; combined score = 7.86), FKBP1A was co-expressed with key p53-regulated apoptotic genes including BAX, BAK1, and TAX1BP3.

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