Barely Significant
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Extreme QTL mapping enables the identification of novel zinc toxicity response loci in Drosophila melanogaster.

Genetics · 2025 · PMC12606420 · PMID 40839771

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nominally significantP < 0.05actually significant
In order to focus on the most interesting gene knockdown effects, RNAi “hits” for a given phenotype were called when the genotype-by-treatment interaction for at least one ANOVA was significant at P < 0.0003 (=0.05/(21 × 4 × 2), since we tested 21 different UAS-RNAi genotypes, against 4 controls, for 2 phenotypes), the interaction was at least nominally significant ( P < 0.05) for the other 3 ANOVAs, and the direction of the effect was consistent over the 4 tests.

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